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    20 July 2018, Volume 27 Issue 3 Previous Issue    Next Issue
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    Editorial
    Condylar adaptation triggered by SGTB orthopedic therapy-Biological mechanism and clinical significance
    SHEN Gang.
    2018, 27 (3):  225-229.  doi: 10.19439/j.sjos.2018.03.001
    Abstract ( 912 )  
    Endochondral ossification constitutes biological and phenotypic foundation for condylar growth. Adaptive response of condylar cartilage to mandibular advancement, on the other hand, facilities condylar remodeling generated by SGTB (sagittal-guided twin block)orthopedic therapy. This enables SGTB to correct increased overjet and overbite by eliminating jaws discrepancy. It is also an encouraging advance that SGTB therapy is used to intervene temporo-mandibular joint disorders (TMD) by regenerating the degraded condylar cartilage.
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    Original Articles
    Expression of Forkhead boxO1 and Runt-related transcription factor 2 in periodontal tissue during orthodontic movement of teeth in rats
    ZHOU Can, LONG Si-cen, HUANG Lan, DAI Hong-wei.
    2018, 27 (3):  230-234.  doi: 10.19439/j.sjos.2018.03.002
    Abstract ( 279 )  
    PURPOSE: To investigate the expression of FoxO1 and Runx2 in periodontal tissue and their effect during orthodontic teeth movement(OTM) in rats. METHODS: Forty 8-week old male Sprague-Dawley (SD) rats were used to establish animal models of orthodontic teeth movement and divided into 5 groups randomly. The right side of jaws of each rat was set as experimental side, and the left side as control side. At 1, 3, 5, 7, 14 d after orthodontic treatment, the rats were sacrificed and the maxillary bone containing the first molar was dissected. H-E staining and immunohistochemical staining were used to detect the morphological changes, the expression of FoxO1 and Runx2 of the periodontal tissue at different points. Computer image analysis was used to evaluate the expression of FoxO1 and Runx2 in the periodontal tissues of the rats. The differences were analyzed by using SPSS19.0 software package. RESULTS: The expression of FoxO1 in periodontal ligament was mainly in osteoblasts and cementoblasts; and the expression of Runx2 was mainly in osteoblasts, fibroblasts and cementoblasts. In the experimental group,the expressions of FoxO1 and Runx2 in the periodontal tissues of rats increased significantly, reached the peak within 3-5 days, then decreased. There was no significant difference between the experimental group and the control group at 14th day (P>0.05), but significant difference was found between other group and control group (P<0.05). CONCLUSIONS: FoxO1 and Runx2 play a role in the reconstruction of periodontal tissue during orthodontic movement of teeth, and they are mainly involved in the process of osteoblast formation and bone formation.
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    Effect of catalase on marginal microleakage of resin restoration after external bleaching
    HAN Yan-yan, WU Tian-tian, ZHU Ya-qin
    2018, 27 (3):  235-238.  doi: 10.19439/j.sjos.2018.03.003
    Abstract ( 246 )  
    PURPOSE: To investigate the effect of catalase on marginal microleakage of resin restoration after external tooth bleaching with 10% carbamide peroxide. METHODS: Forty extracted human premolars, both intact and health, were randomly divided into 4 groups: group 1, direct composite resin filling without bleaching; group 2, composite resin filling immediately after external bleaching; group 3, immersed in artificial saliva for 3 weeks after external bleaching ,then filling with composite resin; group 4 ,cavity treated with catalase after external bleaching and then filled with composite resin. After 2000 thermal cycles, the teeth were immersed in 2% methylene blue for 24 hours, then the microleakage of interface of resin restorations was observed under stereomicroscope. The data were analysed with SPSS17.0 software package. RESULTS: Group 1 displayed the least amount of microleakage, while group 2 showed the greatest amount of microleakage, group 3 behaved similarly as group 2, having great amount of microleakage, with no significant difference (P>0.05); the microleakage of group 4 decreased significantly (P<0.05) compared to group 2. CONCLUSIONS: The microleakage increases significantly after external bleaching with 10% carbamide peroxide, then decreases if cavities are treated with catalase, but delay filling can not improve microleakage effectively.
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    Effect of fluoride-resistant strains of Streptococcus mutans on the bonding strength of dental resin composite
    WANG Jia, HE Zhi-yan, RAN Shu-jun, ZHU Lai-kuan.
    2018, 27 (3):  239-243.  doi: 10.19439/j.sjos.2018.02.004
    Abstract ( 162 )  
    PURPOSE: The aim of this study was to determine the influence of fluoride-resistant strains of S. mutans on the bonding strength of dental resin composite. METHODS: Standardized specimens of resin composite (Z350), and self-etch adhesives (Single bond Universal, 3M) were incubated with S. mutans UA159, fluoride-resistant strains of S. mutans UA159 (UA159-FR) or uninoculated culture medium (Control) or PBS for up to 14 days. Resin-dentin bonded disks were subjected to push-out test. Fractured surface analysis of the specimens was performed by scanning electron microscopy(SEM). SPSS18.0 software package was used for statistical analysis. RESULTS: UA159-FR and UA159 were shown to decrease the bond strengths in levels comparable with those found in the control groups (P<0.05). SEM confirmed the increased degradation of all materials with UA159-FR and UA159, compared with control and PBS. CONCLUSIONS: The results suggest that resin-dentin interface can be compromised by oral bacteria that contribute to the progress of secondary caries. Fluoride-resistant strains of S. mutans and its parental strains both decrease bonding strengths in a short time, but no significant difference in the extent of damage.
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    Analysis of the biocompatibility of a new PLGA/fish skin collagen conjugated electrostatic spinning film
    LU Xiao-li, MIAO Hui-ling, LIU Feng, GAO Mei-qin
    2018, 27 (3):  244-247.  doi: 10.19439/j.sjos.2018.03.005
    Abstract ( 209 )  
    PURPOSE: To study the biocompatibility of a new polylactic acid-glycolic acid(PLGA)/fish skin collagen conjugated electrostatic spinning film. METHODS: PLGA and medical-grade fish skin-I collagen were used as raw materials to prepare nanometer fiber films by conjugated electrostatic spinning technique. Mouse fibroblast L929 was used as a model to evaluate its cell and histocompatibility, which provided experimental basis for application in guided bone regeneration (GBR). RESULTS: Fibroblasts showed good adhesion and growth on the surface of fiber membrane; there were a large number of deep pseudopodias, which were arranged along the orientation of fibers. CONCLUSIONS: PLGA/fish skin collagen conjugated electrostatic spinning membrane is beneficial to fibroblast growth and is expected to be used for GBR.
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    Influence of tribochemical silica coating on shear bond strength of a dental zirconia ceramic to resin cements
    CHENG Hong, DONG Cong, ZHANG Fu-qiang.
    2018, 27 (3):  248-251.  doi: 10.19439/j.sjos.2018.03.006
    Abstract ( 242 )  
    PURPOSE: To evaluate the effect of tribochemical silica coating for zirconia bonding. METHODS: Sixty cut and fully sintered Lava frame zirconia blocks were randomly divided into 6 groups and subjected to 3 different surface treatments and 2 kinds of resin cement.The surface treatments were airborne-particle abrasion/silane, airborne-particle abrasion/CoJet Sand (tribochemical silica coating) /silane and no treatment(control), resin cements were RelyX Unicem and Panavia F2.0. Half of the specimens in each group were randomly chosen and stored in 37℃ distilled water for 24h, the others were thermocycled (5℃ and 55℃) for 5000 cycles. All specimens were subjected to shear bond strength(SBS) testing. SBS values were analyzed by two-way ANOVA and t test, and multiple pairwise comparisons were then completed with post hoc Tukey test. Statistical analysis was performed using SPSS23.0 software package for Windows. RESULTS: Airborne-particle abrasion/CoJet sand/silane group resulted in a significantly higher SBS than those in other groups (P<0.001). After thermocycling, the bond strengths in the airborne-particle abrasion/CoJet Sand/silane groups bonded with RelyX Unicem showed no significantly decrease while marked drop appeared in all other groups. CONCLUSIONS: Combination of tribochemical silica coating with silane coupling can effectively enforce the bond strengths of zirconia (Y-TZP). Attention should be paid to the interaction between surface treatments and resin cements.
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    Hydrogen rich water attenuates pregnancy gingivitis induced by ligation in SD rats
    SHI Yun-zhi, JIN Song, ZHENG Hui-hui, QIN Han, SONG Guo-hua, QIN Shu-cun.
    2018, 27 (3):  252-256.  doi: 10.19439/j.sjos.2018.03.007
    Abstract ( 220 )  
    PURPOSE: To investigate the effect of hydrogen rich water on experimental gingivitis in SD rats during pregnancy. METHODS: Female SD rats mated with male ones were chosen to induce experimental gingivitis after ligation for 2 weeks. The pregnant rats were randomly divided into control group, model group and HW group. In the control and model group, rats were given pure water, while animals in the HW group were given hydrogen-rich water twice a day. All pregnant animals were sacrificed on day 16 of pregnancy. The level of Prog, SOD and TNF-α in the gingiva of different groups were measured by ELISA, the expression of PR, NFκB and TNF-α were determined by immunohistochemistry and Western blot. SPSS 13.0 software package was used for data analysis. RESULTS: Pregnancy gingivitis of SD rats could be induced by thread ligation. PR was mainly distributed in the gingival epithelium, while there was no significant difference of Prog and PR in the gingiva among different groups(P>0.05). Furthermore, in the model group, lower SOD level as well as higher NFκB and TNF-α level were found in the gingiva. Compared with the model group, the inflammatory response of pregnancy gingivitis in HW group was significantly suppressed along with decreased NFκB and TNF-α. CONCLUSIONS: Progesterone and its receptor may play an indirect role in the process of pregnancy gingivitis of rats. Hydrogen rich water may be beneficial in suppressing pregnancy gingivitis progress by decreasing inflammatory response related to gingival oxidative stress.
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    Comparative study of enamel discoloration related to bonding with different orthodontic adhesives and cleaning-up with different procedures
    WU Hai-miao, YE Cui, CHEN Dong.
    2018, 27 (3):  257-260.  doi: 10.19439/j.sjos.2018.03.008
    Abstract ( 414 )  
    PURPOSE: The aim of this study was to compare if there was any difference in the enamel discoloration after staining when three orthodontic adhesives and 4 enamel clean-up methods were tested. METHODS: Three types of orthodontic adhesives were used: chemically cured resin, light-cured resin and resin-modified glass-ionomer cement. A total of 120 human extracted premolars were included. Ten teeth of each orthodontic adhesive were randomly cleaned-up with 1 of 4 different procedures and stained in coffee for 7 days: carbide bur (TC), carbide bur and Sof-Lex polishers (TC+SL), carbide bur and One Gloss polishers (TC+OG), carbide bur and PoGo polishers (TC+PG). Colour measurements were made with Crystaleye dental spectrophotometer at baseline and after storage in a coffee solution for 1 week. Two way ANOVA and Bonferroni test were used for statistical analysis with SPSS 13.0 software package. RESULTS: The colour change values of adhesive materials in the TC group were the greatest. The lowest ΔE* values were obtained from the TC+SL group. However, there was no significant difference between the TC+SL and TC+PG group (P>0.05). The resin-modified glass-ionomer cement group showed the lowest colour differences and chemically cured resin group showed the highest ΔE* values among all orthodontic adhesives (P<0.05). CONCLUSIONS: The colour change of enamel surface is affected by the type of adhesive materials and clean-up procedures.
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    Effect of anti-inflammatory flavonoid chrysin on osteogenesis of preosteoblast MC3T3-E1 cells
    XIA Bing, HONG Tao, HE Xin.
    2018, 27 (3):  261-264.  doi: 10.19439/j.sjos.2018.03.009
    Abstract ( 242 )  
    PURPOSE: To investigation the effect of flavonoid chrysin on osteogenesis of preosteoblast MC3T3-E1 cells. METHODS: After evaluation of the toxic effect of chrysin, preosteoblast MC3T3-E1 cell suspension was prepared with DMEM and then the cells were cultured with 0 and 25 μmol/L chrysin. Real-time quantitative PCR was used to detect the expression of osteogenic marlcers including Runx2, ColA1 and OCN. Statistical analysis was performed using SPSS17.0 software package. RESULTS: 25 μmol/L chrysin had no toxic effect on preosteoblast MC3T3-E1 cells. After co-culture with 25 μmol/L chrysin,the expression of Runx2, ColA1 and OCN was highest at the 7th,14th and 21th day,respectively.CONCLUSIONS: : 25 μmol/L chrysin can promote osteogenic gene expression of preosteoblast MC3T3-E1 cell.
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    miR-199b-5p inhibits proliferation and invasion of head and neck cancer cells
    WANG Xi, LI Guang-hui, GUO Jia, SUN Qiang.
    2018, 27 (3):  265-269.  doi: 10.19439/j.sjos.2018.03.010
    Abstract ( 182 )  
    PURPOSE: This study identified the differentially expressed miR-199b-5p in the progressing of head and neck squamous cell carcinoma(HNSCC) and investigated its biological characters. METHODS: The expression of miR-199b-5p in 128 HNSCC tissues samples was evaluated. The association between clinicopathological parameters and the expression levels of the candidated miRNAs was analyzed by using Kaplan-Meier survival analysis. Cell growth, invasion and migration potential, and clone formation were observed to detect the functions of the miRNAs in HNSCC cells. Statistical analysis was performed using SPSS 19.0 software package. RESULTS: In 79 HNSCC tissues with cervical lymph node metastasis, the expression level of miR-199b-5p was 1.68±0.21; while the expression level was 2.64±0.24 in 28 tissues without lymph node metastasis (P=0.001). In patients with HNSCC, lower level of miR-199b-5p expression significantly correlated with worse overall survival rate (P=0.01). Overexpression of miR-199b-5p inhibited HNSCC cell proliferation and invasion. CONCLUSIONS: miR-199b-5p plays a key role in cell invasion and metastasis and its expression correlated with overall survival in patients with HNSCC.
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    Changes of upper airway in ClassⅡchildren with high mandibular plane angle before and after functional treatment by high headgear-activator
    XIA Song, DAI Hong-wei, ZHANG Yi, WANG Chao, QIU Liang-xing, WANG Hua-qiao.
    2018, 27 (3):  270-274.  doi: 10.19439/j.sjos.2018.03.011
    Abstract ( 844 )  
    PURPOSE: This study was performed to investigate the changes of upper airway before and after functional correction in ClassⅡmalocclusion children with high mandibular plane angle at growth and development peak. METHODS: Cone-beam CT (CBCT) data of the upper airway were inputted into Minics 17.0 software for measurement of changes in the upper airway before and after functional treatment by high headgear-activator. The changes of upper airway before and after treatment were analyzed with SPSS22.0 software package. RESULTS: The change of the total volume of the upper airway, the volume of the velopharynx, glossopharynx, laryngopharynx; the sectional area of the tip of soft palate, roof of the epiglottis, the minimum sectional area of the oropharynx were significant (P<0.05). The upper airway morphology tended to be circular in the soft palate tip plane(P<0.05), but there was no significant difference in the plane of epiglottis(P>0.05). CONCLUSIONS: High headgear-activator corrected mandibular hypoplasia in children with increased airway volume, increased ventilation, improved respiratory function to prevent occurrence of obstructive sleep apnea hypopnea syndrome after adult.
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    Effects of Dnmt1 and Dnmt3b in mucoepidermoid carcinoma of salivary glands
    WANG Zhi-ming, WANG Xing-ao, ZHANG Shi-kun, WANG Xi-zhong, WANG Li, ZHANG Xin-yue,LIU Nan-nan,TANG Yan-yan.
    2018, 27 (3):  275-279.  doi: 10.19439/j.sjos.2018.03.012
    Abstract ( 238 )  
    PURPOSE: To investigate the effects of DNA methyltransferase in mucoepidermoid carcinoma of human salivary glands tissues. METHODS: Forty-three samples from mucoepidermoid carcinoma of salivary glands and 17 normal salivary gland tissues were collected from January 2010 to September 2013. Immunohistochemistry and Western blot were used to detect the expression of Dnmt1 and Dnmt3b in normal tissues and specimen of mucoepidermoid carcinoma of salivary glands. The data were analysed with SPSS 22.0 software package. RESULTS: The positive expression rate of Dnmt1 in mucoepidermoid carcinoma tissue was 37.21%, and that in normal salivary gland tissues was 17.65%, there was no significant difference between them; the positive expression rate of Dnmt3b in mucoepidermoid carcinoma tissue was 83.72%, which was significantly higher than that in normal salivary gland tissue (11.76%, P<0.01). However, there was no significant correlation between high expression of Dnmt1 and Dnmt3b and clinicopathological parameters. CONCLUSIONS: Dnmt3b may play a role in the tumorigenesis of mucoepidermoid carcinoma in salivary glands.
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    Evaluation of the effects of two different modes of orthognathic surgery on upper airway morphology in patients with skeletal Class Ⅲ malocclusion
    NIE Ping, TAO Li, ZHU Yan-fei, SUN Hui-jun, ZHU Min.
    2018, 27 (3):  280-284.  doi: 10.19439/j.sjos.2018.03.013
    Abstract ( 276 )  
    PURPOSE: To establish three-dimensional models of upper airway pre- and post-orthognathic surgery in patients with skeletal Class Ⅲ malocclusion, and to compare the effects of different modes of orthognathic surgery on the cross-sectional areas and volumes of upper airway. METHODS: Twenty-eight patients with skeletal Class Ⅲ malocclusion were divided into 2 groups. Group A (12 patients) underwent bilateral sagittal split ramus osteotomy(BSSRO) for mandibular setback, named single jaw surgery group; group B (16 patients) underwent BSSRO + Le Fort I osteotomy for mandibular setback and maxillary advancement, named bimaxillary surgery group. All patients received CT scanning before (T1) and 3 months after surgery (T2). The three-dimensional models of the upper airway containing velopharynx, glossopharynx and laryngopharynx were established by using Dolphin Imaging 11.7 software. The changes of sagittal diameters, coronal diameters, cross-sectional areas and volumes of the upper airway were measured and compared between the two groups pre- and post- surgery (T1, T2) using SPSS 16.0 software package, respectively. RESULTS: In velopharynx, the values of group A were decreased after surgery, while the other values of group B were increased except the value of coronal diameter. There was a significant difference between the two groups (P<0.05). In glossopharynx and laryngopharynx, the values of group A and group B were both decreased after surgery. The reduction of the cross-sectional areas and volumes in group A were more obvious than group B (P<0.05). CONCLUSIONS: The amount of narrowing of the upper airway is smaller in patients undergoing bimaxillary surgery than in patients undergoing mandibular setback surgery.
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    Impact of oral health promotion project on periodontal condition and life quality of the elderly in long-term care institutions
    LI Xiao-li, LIU Ming-yu, CHENG Liang, ZHU Hong-fei, SHANG Shu-huan, CUI Dan.
    2018, 27 (3):  285-288.  doi: 10.19439/j.sjos.2018.03.014
    Abstract ( 260 )  
    PURPOSE: To assess the impact of oral health promotion project on periodontal condition and life quality of the elderly in long-term care institutions. METHODS: Elder people from 5 nursing homes in Wuhan city were selected and assigned to either the experimental group or the control group by random cluster grouping method. A six-month oral health promotion project was provided to the experimental group. The changes of geriatric oral health assessment index (GOHAI), oral hygiene index-simplified (OHI-S), gingival index (GI), bleeding on probing (BOP) and probing depth (PD) were compared with student's t test and repetitive measure analysis of variance using SPSS21.0 software package. RESULTS: A total of 322 subjects completed the study for 6 months, with 144 from the experimental group and 178 from the control group. No significant difference was observed between the two groups in social demographic characteristics, GOHAI scores, OHI-S, GI, BOP and PD at baseline(P>0.05). Greater improvements were observed in GOHAI scores, OHI-S, GI and BOP in the experimental group than the control group after interventions (P<0.05). CONCLUSIONS: Oral health promotion project can improve the elderly's oral health-related quality of life and periodontal condition.
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    A long-term clinical evaluation of comprehensive physiotherapy for patients with chronic anterior disc displacement of the temporomandibular joint without reduction
    FANG Zhong-yi, FAN Shuai, CAI Bin, XU Li-li, JIANG Xin, LIU Li-kun, HE Ying.
    2018, 27 (3):  289-292.  doi: 10.19439/j.sjos.2018.03.015
    Abstract ( 503 )  
    PURPOSE: To observe the long-term clinical efficacy of comprehensive physiotherapy for patients with chronic anterior disc displacement of the temporomandibular joint (TMJ) without reduction (ADDWoR). METHODS: A total of 256 patients with chronic ADDwoR (the course of disease was 8.4±9.6 months) who completed the treatment in our hospital from January 2014 to December 2015 were followed up. Symptoms and function pre-treatment, post-treatment and during follow-up including the maximum active mouth opening (mm), visual analog scale(VAS), mandibular function impairment questionnaire (MFIQ) score were recorded and compared; recurrent frequency and symptoms were recorded and compared, too. SPSS 17.0 software package was used for analysis of variance of repeated measurement. RESULTS: The follow-up period was 30.5±4.6 months, the patients' maximum mouth opening: pre-treatment post-treatment> follow-up (P<0.05); the patients' MFIQ: pre-treatment>post-treatment> follow-up (P<0.05). 82.8% patients didn't have recurrent symptoms, 14.5% had recurrence and the symptoms were not improved in 2.7% of patients. Among 37 patients with symptomatic recurrent disease, 70.3% had pain, 13.5% had mouth opening limitation, and 13.6% had pain with mouth opening limitation. CONCLUSIONS: Comprehensive physical therapy can significantly relieve pain and improve mouth limitation in patients with chronic ADDwoR of TMJ, and long-term efficacy was good. The causes of recurrence in some patients need further study.
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    Analysis of caries and its risk factors of the first permanent molar among primary school students in Pudong, Shanghai and Lichuan, Jiangxi Province
    SU Hong- ru, QIAN Wen-hao, ZHANG Yan.
    2018, 27 (3):  293-297.  doi: 10.19439/j.sjos.2018.03.016
    Abstract ( 360 )  
    PURPOSE: To Investigate the current situation of caries of primary school students in Shanghai Pudong and Lichuan, Jiangxi province, and analyze the risk factors of dental caries, in order to provide scientific evidence for prevention and treatment of dental caries. METHODS: A stratified cluster sampling method was applied to choose 10 primary schools from Lichuan and 2 primary schools from Pudong area, respectively. A total of 1922 pupils aging from 6 to 12 were selected. Oral health examination was applied to each student and questionaire survey was conducted among their parents. The results were analyzed with SPASS 21.0 software package. RESULTS: Two hundred and sixty-one caries was found in Lichuan pupils, with the caries rate of 23.6% and DMFT being 0.37±0.766. 96 caries was found in Pudong pupils, with the caries rate of 11.8% and DMFT being 0.19±0.582. There was significant difference between two areas. Analysis of risk factors showed a significant correlation between children's pre-bedtime sweets and other bad habits, as well as low level of education of children's parents and dental caries. CONCLUSIONS: The caries of primary school students in rural areas are significantly worse than those in urban areas; bad living habits are risk factors of caries and the knowledge of caries prevention should be popularized in school students to enhance the awareness of oral health among pupils.
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    Evaluation of the clinical effect of fluoride coating combined with pit and fissure sealing or preventive resin filling on prevention of first permanent molars caries
    XU Yan, WU Qing-ju, LUO Li-ping, JIN Shi-qing.
    2018, 27 (3):  298-301.  doi: 10.19439/j.sjos.2018.03.017
    Abstract ( 216 )  
    PURPOSE: To explore the clinical effect of fluoride coating combined with pit and fissure sealing or preventive resin filling on prevention of young first permanent molars caries. METHODS: Three hundred suspicious first permanent molars caries in 90 children (6-8 years old) who received oral health examination in our hospital from February 2015 to January 2016 were included as the study subject, and randomly divided into group A, B, C, D and E. Group A received pit and fissure sealing, group B received preventive resin filling, group C received 0.5% fluoride coating combined with pit and fissure sealing, group D received 0.5% fluoride combined with preventive resin filling, group E as control group with nursing daily brushing. 6, 12 and 18 months after treatment, caries rate in each group was evaluated and preservation of pit and fissure sealing or resin filling in group A, B, C, D was examined. The data were analyzed using SPSS 21.0 software package. RESULTS: Six and 12 months after treatment, there was no significant difference (P>0.05) in the preservation rate of pit and fissure sealing or resin filling and caries rate in group A, B, C, D. Eighteen months after treatment, caries rate in group E was significantly higher than that of group A, B, C, D; there was significant difference between group A and group C, group B and group D (P<0.01); caries rate of group A, B was relatively high, the preservation rate was lower than that of group C and D, the differences were statistically significant (P<0.05). CONCLUSIONS: For suspected young permanent molars caries, fluoride coating combined with pit and fissure sealing or separate pit and fissure sealing has a certain effect on prevent dental caries, but the fluoride coating combined with preventive resin filling is better.
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    Application of panoramic film in predicting orthodontic treatment time for impacted maxillary canine
    LIN Yan, MA Guang-li, YE Li-li, YE Min, LIU Wei-dong, JIANG Yin-hua.
    2018, 27 (3):  302-304.  doi: 10.19439/j.sjos.2018.03.018
    Abstract ( 313 )  
    PURPOSE: To evaluate the influence of pretreatment radiographic features (angle, distance, and location) on the duration of active orthodontic traction. METHODS: Sixty maxillary unilateral impacted canines were selected to analyze the panoramic features(angle, line spacing, and location) in pre-treatment patients, the results were evaluated using SPSS19.0 software package for multivariate regression analysis. RESULTS: Pretreatment radiographic variables (angle, line spacing, and location) were significantly associated with the duration of orthodontic traction. The sex and site of impaction did not significantly affect the duration of traction. CONCLUSIONS: Impacted canine angle, distance and position can predict the orthodontic traction time.
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    Efficacy of Nd:Yap laser combined with composite resin for restoring hypersensitive wedge-shaped defect in 70 patients
    HE Hong, WANG Yi.
    2018, 27 (3):  305-308.  doi: 10.19439/j.sjos.2018.03.019
    Abstract ( 232 )  
    PURPOSE: The purpose of this study was to explore the effect of Nd:Yap laser combined with composite resin filling on reducing hypersensitivity of dental wedge-shaped defect. METHODS: Seventy cases, 144 teeth with sensitive wedge-shaped defects were selected. The patients were randomly divided into 2 groups and treated as below: 35 cases, 74 teeth in group A were treated with composite resin directly; 35 cases, 70 teeth in group B were treated with Nd:Yap laser combined with composite resin. After treatment, the effective rates under clinical examination standard (immediately, 1, 3 and 6 months after treatment) in both groups were collected and statistically analysed with SPSS 13.0 software package. RESULTS: In group A, one and 2 teeth fillings fell off 3 months and 6 months after treatment,respectively. In group B, one and 1 tooth fillings fell off 3 months and 6 months after operation. There was no significant difference between the two groups (P>0.05). The effective rates of desensitization were 95.71%,91.43%,87.14% and 81.43% in group B, respectively, which were significantly higher than those in group A (82.43%,78.38%,72.97% and 64.86%)(P<0.05). CONCLUSIONS: Nd:Yap laser combined with composite resin filling can treat sensitive wedge-shaped defect effectively and improve the symptoms of tooth sensitivity significantly .
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    Expression of miR-146a in saliva of chronic periodontitis patients and its influence on gingival crevicular inflammation and MMP-8/TIMP-1 levels
    GAO Ying, HAO Chen-di.
    2018, 27 (3):  309-312.  doi: 10.19439/j.sjos.2018.03.020
    Abstract ( 186 )  
    PURPOSE: To study the expression of miR-146a in saliva of chronic periodontitis patients and its influence on gingival crevicular inflammation and MMP-8/TIMP-1 levels. METHODS: Sixty-eight patients with chronic periodontitis treated in our hospital during March 2015 to January 2017 were chosen as the experimental group, while 50 healthy volunteers for physical examination were chosen as the control group. The level of miR-146a in saliva and inflammatory factors, MMP-8/TIMP-1 in gingival crevicular fluid were detected. Pearson test was used to assess the correlation between expression of miR-146a in saliva and the severity of disease with SPSS24.0 software package. RESULTS: The expression of miR-146a in saliva in the experimental group was significantly higher than that in the control group(P<0.05). The level of inflammatory cytokines (IL-1β, IL-6 and IL- 35, TNF-α), the indexes of periodontal clinical symptoms (PD, AL, PLI, BI) in the experimental group were significantly higher than those in the control group (P <0.05); and MMP-8 and TIMP-1 in gingival crevicular fluid in the experimental group were significantly higher than those in the control group(P<0.05). Pearson test found that the expression of miR-146a in saliva of patients with chronic periodontitis was positively correlated with the degree of gingival inflammation, the severity of periodontal symptoms and the level of MMP-8/TIMP-1. CONCLUSIONS: The expression of miR-146a in saliva of chronic periodontitis patients is abnormally high, and the specific expression is consistent with the degree of gingival inflammation and periodontal injury.
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    A clinical investigation of plaque control efficacy and safety of Sonicare toothbrush in children
    ZHAO Shi-min, CHEN Hui, YU Ping-bo, WANG Jun.
    2018, 27 (3):  313-317.  doi: 10.19439/j.sjos.2018.03.021
    Abstract ( 297 )  
    PURPOSE: To provide theoretical basis for children's oral health instruction and children's dental prophylaxis by comparing the plaque control efficacy and safety of Sonicare and manual toothbrush in 3-9 years old children. METHODS: One hundred and eighty healthy children were included in this study and were divided into 2 groups with 90 children in each group: aged 3-6 years and 6-9 years respectively. In each group, the subjects were randomly instructed to use either Sonicare for kids (SFK) or manual tooth brush (MTB). During a 28-day clinical trial period, oral hygiene was examined and plaque index(Rustogi modified Navy plaque index,RMNPI) was recorded at baseline, and at visits on the 7th and the 28th day (D0, D7, D28). The data were analyzed by R software. RESULTS: Both MTB and SFK could remove a certain amount of dental plaque. In the group of 3-6 years old children, the plaque reduction rates of children using SFK were 17.09%±14.4%(D0), 27.14%±11.4%(D7), 33.52%±18.3%(D28), respectively, which were significantly higher than that of children using MTB [11.86%±9.7%(D0), 11.83%±9.1%(D7), 13.73%±11.0%(D28)] (P<0.05). Similarly, in the group of 6-9 years old children, the plaque reduction rates of children using SFK were 20.05%±10.52%(D0), 22.76%±13.46%(D7), 22.31%±9.74% (D28), which were significantly higher than that of children using MTB [9.15%±7.07%(D0), 7.26%±6.81%(D7), 11.54%±8.27%(D28)] (P<0.05). Further analysis revealed that the plaque index was decreased gradually in 3-6 years old children using SFK after 3 months of follow-up (P<0.05). In addition, there was better compliance and safety in children using SFK. CONCLUSIONS: Sonicare can remove plaque efficiently, and can control plaque and improve oral hygiene quality effectively in children in a long period, which implies that the application of Sonicare is worthy of promoting to control dental plaque in children.
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    Effect of full crown preparation with ultrasound instrument on marginal adaption: a randomized controlled trial
    XU Xiao-bo, HOU Yong-fu,BIAN Hua-qin,WANG Mian, HUANG Yan.
    2018, 27 (3):  318-321.  doi: 10.19439/j.sjos.2018.03.022
    Abstract ( 248 )  
    PURPOSE: To study the effect of full crown ultrasound preparation on crown margin. METHODS: Thirty-two patients with 35 units of full crown were randomly divided into 2 groups. Teeth in the experimental group were prepared with ultrasound diamond instrument while teeth in the control group were prepared with a high-speed hand piece with regular diamond burs. Teeth in both groups were restored using Zirconia full ceramic crowns. Then all patients were evaluated for morphology of finishing line, marginal adaptation and marginal gingival coloration in the proximal side after 6-month of follow-up, respectively. SPSS17.0 software package was used for statistical analysis. RESULTS: Marginal adaptation did not show significant difference between the experimental and control group (P>0.05). Morphology of finishing line and marginal gingival coloration in the proximal side showed significant difference (P<0.05). CONCLUSIONS: It is recommended to perform tooth preparations with ultrasound diamond instruments, which may produce significantly less marginal gingival coloration in the proximal margin after 6-month of follow-up.
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    Role of corticotomy in assisting space closure with atrophic alveolar ridge
    QIN Fei, MA Xiao-qing, XIANG Fei.
    2018, 27 (3):  322-325.  doi: 10.19439/j.sjos.2018.03.023
    Abstract ( 206 )  
    PURPOSE: To study the effect of corticotomy in assisting space closure in cases whose alveolar ridge atrophy was obvious after extraction. METHODS: Twenty two cases whose canine's distal movement<0.2mm/m were selected, 12 accepted corticotomy and the other 12 were selected as the control group. All the spaces were closed with sliding mechanics under the help of microscrews. SPSS 13.0 software package was used for statistical analysis. RESULTS: All the spaces were closed. The canine's movement speed in the experimental group was superior to the control group(P<0.05), and the canine's movement was almost bodily movement (P<0.05); there was no obvious gingiva fold after space closure (P<0.05). There was no significant difference in the sulcus depth on the distal surface of the upper canine(P>0.05). CONCLUSIONS: Corticotomy is helpful to space closure in cases with significant alveolar ridge atrophy.
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    Data Analysis
    Analysis of articles published in Shanghai Journal of Stomatology form 2012 to 2016
    LI Xue-lu, XU Ling.
    2018, 27 (3):  326-332.  doi: 10.19439/j.sjos.2018.03.024
    Abstract ( 191 )  
    PURPOSE: To analyze the advantages and disadvantages of Shanghai Journal of Stomatology(SJOS), and provide some suggestions for its sustainable development. METHODS: The volumes, issues, the first authors, author affiliation, date of reception, fund, the frequency of cited and downloaded articles published in SJOS from 2012 to 2016 were recorded. The data were analyzed by bibliometric methods. RESULTS: Seven hundred and eighty-nine papers were published in SJOS in 5 years. The total number of the first authors was 702, which were distributed in 29 provinces, autonomous regions or municipalities. All 789 papers were from 222 research institutions, key laboratory, medical universities and their affiliations. 37 papers (4.69%) were written by the first authors in top 10, while 88 papers (11.15%) by the corresponding authors in top 10. 118/789 (14.96%) were funded by national projects and 339/789 (42.97%) by regional projects. The average time of delay in publication of articles (DPA) was 282.44 days (9.41 months) in 5 years. 615/789 (77.95%) papers were cited, the total frequency of cited and downloaded articles were 2388 and 75866, respectively. The impact factors were increased year by year gradually. CONCLUSIONS: SJOS has strong academic influence in the field of stomatology with a core group of authors, and highly recognized in society.
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    Dental Education
    Application and exploration of micro-class combined with flipped classroom in cardiopulmonary resuscitation teaching for dental students
    ZHU Hong, YAN Xiao-lei, SHEN Dao-jie, ZHANG Su-ning,HUANG Jing.
    2018, 27 (3):  333-336.  doi: 10.19439/j.sjos.2018.03.025
    Abstract ( 283 )  
    PURPOSE: To explore the application of micro-class combined with flipped classroom in cardiopulmonary resuscitation teaching for dental students. METHODS: The experimental group included 46 students from grade 2014 in college of stomatology, Shanghai Jiao Tong University. The control group included 45 students from grade 2013. Students in the control group were taught in traditional method, while those in the experimental group were taught in micro-class combined with flipped classroom teaching. After the course, we compared the outcome of didactic test and skill evaluation about CPR. A questionnaire survey was conducted in the experimental group. SPSS16.0 software was employed for statistical analysis. RESULTS: The results of didactic test and skill evaluation in the experimental group was significantly better than that in the control group(P<0.05). The results of questionnaire showed that application of micro-class combined with flipped classroom was appreciated by over 80% students. CONCLUSIONS: The implementation of micro-class combined with flipped classroom can achieve a better teaching effect in cardiopulmonary resuscitation teaching for dental students.
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