Comparative study of sensitivity of different dental metal materials

Abstract

Abstract: PURPOSE: To compare the sensitivity of different dental metal materials, in order to provide references for choosing of dental metal materials. METHODS: Patch test was performed on 92 patients wearing dental metal prosthesis. Pearson Chi-square test, corrected Chi-square test and Fisher exact test were used for statistical analysis with SPSS17.0 software package. RESULTS: ①The sensitivity rates of different metal materials were different. The allergy rate of nickel (Ni) was the highest (22.8%), while the allergy rate of aluminum (Al) was 0. ②More women were allergic to both palladium (Pd) and nickel (Ni) than men with significant difference (P>0.05). ③Women with ear piercing were more allergic to nickel (Ni), but there was no significant correlation between ear piercing and nickel allergy (P>0.05).④There was cross reaction between nickel(Ni)and palladium (Pd), 83.3% of palladium (Pd) allergy patients were allergic to nickel (Ni), while 47.6% of nickel(Ni) allergy patients were allergic to palladium (Pd). ⑤Patch test had a delayed reaction. CONCLUSIONS: Dental metal materials have certain allergies, women are more allergic to both palladium (Pd) and nickel (Ni) than men, with significant difference. Patch test may have a delayed reaction. If necessary, observation for 96 h, 7 days or even longer time, are needed to exclude false positivity.

Key words: Dental metal materials, Patch test, Allergic reactions

CLC Number:

R783.1

LIU Yue, WANG Xiao-ping, WU-Bin, HU-Yue, DOU Xia, SUN Hong-ying, DING Ya-tong, ZHANG Xin. Comparative study of sensitivity of different dental metal materials[J]. Shanghai Journal of Stomatology, 2014, 23(2): 143-148.

References

[1] 赵铱民.口腔修复学[M]. 第6版. 北京:人民卫生出版社, 2008: 2.
[2] 苏润刚, 李春华, 钱烨. 牙科用铬合金在不同pH值的人工唾液中耐腐蚀性能的研究 [J]. 华西口腔医学杂志, 2010, 28(1): 34-37.
[3] 刘贤, 孙皎. 采用一种新型动态力加载装置研究力对镍铬烤瓷合金中镍离子释放的影响[J]. 医用生物力学, 2011, 26(3): 247-251.
[4] Hosoki M, Bando E, Asaoka K, et al. Assessment of allergic hypersensitivity to dental materials [J]. Biomed Mater Eng, 2009, 19(1): 53-61.
[5] Schalock PC, Menné T, Johansen JD, et al. Hypersensitivity reactions to metallic implants-diagnostic algorithm and suggested patch test series for clinical use[J]. Contact Dermatitis, 2012, 66(1): 4-19.
[6] Uter W, R?msch C, Aberer W, et al. The European baseline series in 10 European Countries, 2005/2006-results of the European Surveillance System on Contact Allergies (ESSCA)[J]. Contact Dermatitis, 2009, 61(1): 31-38.
[7] Thyssen JP, Linneberg A, Menné T, et al. The epidemiology of contact allergy in the general population-prevalence and main findings [J]. Contact Dermatitis, 2007, 57(5): 287-299.
[8] Frigerio E, Pigatto PD, Guzzi G, et al. Metal sensitivity in patients with orthopaedic implants: a prospective study [J]. Contact Dermatitis, 2011, 64(5): 273-279.
[9] Sicilia A, Cuesta S, Coma G, et al. Titanium allergy in dental implant patients: a clinical study on 1500 consecutive patients [J]. Clin Oral Implants Res, 2008, 19(8): 823-835.
[10] 沈曙铭, 杨帆. 银汞合金引发掌跖脓疱病1例 [J]. 现代口腔医学杂志, 2012, 26(3): 211-212.
[11] 郑佑祥, 张敏. 镍铬合金全冠过敏症3 例报道 [J]. 临床口腔医学杂志, 2006, 22(1): 35.
[12] 陈治清. 口腔材料学 [M]. 北京: 人民卫生出版社, 2008: 152.
[13] Ameer MA, Khamis E, Al-Motlaq M. Electrochemical behavior of non-precious dental alloys in bleaching agents [J]. Electrochim Acta, 2004, 50(1): 141-148.
[14] Johnson A, Shiraishi T, Al-Salehi SK. Ion release from experimental Au-Pt-based metal-ceramic alloys [J]. Dent Mater, 2010, 26(7): 682 -687.
[15] Qiu J, Yu WQ, Zhang FQ. Effects of the porcelain-fused-to-metal firing process on the surface and corrosion of two Co-Cr dental alloys [J]. J Mater Sci, 2011, 46(5): 1359-1368.
[16] 张荣和, 田绪标. 3种烤瓷熔附金属冠铬在唾液中的离子析出量分析 [J].滨州医学院学报, 2012, 35(4): 269-271.
[17] 于华, 张晓东, 王亦菁, 等. 口腔金属材料安全性、相容性以及功能性的评价[J]. 中国组织工程研究, 2012, 16(47): 8907-8914.
[18] 曹新明, 王珏, 夏刚, 等. 镍铬合金烤瓷冠配戴者尿镍、铬水平和肾功能的关系分析 [J]. 上海口腔医学, 2012, 21(3): 312-316.
[19] 刘雅琼, 欧阳荔, 解清, 等. 镍铬合金烤瓷冠修复患者血液金属含量分析[J]. 中国公共卫生, 2010, 26(2): 248-249.
[20] 樊国彪, 王学民. 诊断性斑贴试验方法学的中文文献分析 [J]. 临床皮肤科杂志, 2011, 40(4): 218-220.
[21] 张学军. 皮肤性病学 [M]. 北京: 人民卫生出版社, 2001: 33.
[22] 曹晓佳, 张理涛. 瑞敏系列和TURE TEST系列斑贴试剂检测结果比较 [J].中国皮肤性病学杂志, 2012, 26(1): 19-21.
[23] Lazarov A, David M, Abraham D, et al. Comparison of reactivity to allergens using the TRUE Test and IQ chamber system [J]. Contact Dermatitis, 2007, 56(3): 140-145.
[24] Schiessl C, Wolber C, Strohal R, et al. Reproducibility of patch tests: comparison of identical test allergens from diferent commercial sources [J]. Contact Dermatitis, 2004, 50(1): 27-30.
[25] 周成霞, 李利. 斑贴试验在皮肤科学中的应用 [J]. 临床皮肤科杂志, 2010, 39(11): 734-735.
[26] 秦鸥, 王学民. 诊断性斑贴试验的临床应用 [J]. 临床皮肤科杂志, 2007, 36(12): 800-802.
[27] Kalimo K, Lammintausta K. 24 and 48 h allergen exposure in patch testing. Comporative study with 11 common contact allergens and NiCl2 [J]. Contact Dermatitis, 1984, 10(1): 25-29.
[28] 薛春霄, 夏宝凤, 孙祥, 等. 职业性皮肤病诊断标准中有关皮肤斑贴试验方法的修订[J].中华劳动卫生职业病杂志, 2000, 18(3): 175-177.
[29] Dotterud LK, Smith-Sivertsen T. Allergic contact sensitization in the general adult population: a population-based study from Northern Norway [J]. Contact Dermatitis, 2007, 56(1): 10-15.
[30] Meijer C, Bredberg M, Fischer T, et al. Ear piercing, and nickel and cobalt sensitization, in 520 young Swedish men doing compulsory military service [J]. Contact Dermatitis, 1995, 32(3): 147-149.
[31] Summer B, Fink U, Zeller R, et al. Patch test reactivity to a cobalt -chromium-molybdenum alloy and stainless steel in metal-allergic patients in correlation to the metal ion release [J]. Contact Dermatitis, 2007, 57(1): 35-39.
[32] 刘丽, 何福明. 牙科合金的应用现状和存在的问题 [J]. 口腔材料器械杂志, 2002, 11(1): 10-13.
[33] Faurschou A, Menné T, Johansen JD, et al. Metal allergen of the 21st century-a review on exposure, epidemiology and clinical manifestations of palladium allergy [J]. Contact Dermatitis, 2011, 64(4): 185-195.
[34] 冯均伟, 王跃, 朱宗, 等. 骨科人工关节置换术后金属过敏研究进展 [J].实用医院临床杂志, 2012, 9(3): 166-169.
[35] Olmedo DG, Paparella ML, Brandizzi D, et al. Reactive lesions of peri-implant mucosa associated with titanium dental implants: a report of 2 cases [J]. Int J Oral Maxillofac Surg, 2010, 39(5): 503-507.