上海口腔医学

上海口腔医学 ›› 2017, Vol. 26 ›› Issue (4): 429-433.doi: 10.19439/j.sjos.2017.04.016

• 论著 • 上一篇    下一篇

下颌骨骨折术后感染相关因素分析

何思铃1, 肖水生2   

  1. 1.重庆医科大学口腔医学院,口腔疾病与生物医学重庆市重点实验室,重庆 401147；
    2.重庆医科大学附属口腔医院 口腔颌面外科,口腔疾病与生物医学重庆市重点实验室,重庆 401147
  • 收稿日期:2017-02-21 修回日期:2017-04-17 出版日期:2017-08-25 发布日期:2017-09-01
  • 通讯作者: 肖水生,E-mail:xiaoss66@hotmail.com
  • 作者简介:何思铃（1986-）,男,硕士研究生,E-mail:769667927@qq.com
  • 基金资助:
    重庆市卫生局医学科研项目(2012-2-122)

Analysis of relative factors associated with postoperative infection of mandibular fractures

HE Si-ling1, XIAO Shui-sheng2   

  1. 1.College of Stomatology, Chongqing Medical University; Chongqing Key Laboratory for Oral Diseases and Biomedical Sciences, Affiliated Hospital of Stomatology. Chongqing 101147;
    2.Department of Oral and Maxillofacial Surgery, Affiliated Hospital of Stomatology, Chongqing Medical University. Chongqing 401147, China
  • Received:2017-02-21 Revised:2017-04-17 Online:2017-08-25 Published:2017-09-01

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摘要： 目的探讨下颌骨骨折行坚固内固定术后与感染相关的危险因素。方法设计病例对照研究,收集我院2009年1月—2015年12月期间下颌骨骨折坚固内固定手术患者447例,其中出现术后感染的病例为26例（实验组）。从每例发生术后感染的患者入院前2周内,随机选取1例下颌骨骨折坚强内固定术后无任何并发症的患者纳入对照组,共26例。收集整理相关的变量数据,采用SAS9.2软件包在2组间行二变量和多因素Logistic回归分析,确定与术后感染相关的因素。结果回归分析结果显示,增长的下颌骨骨折严重程度评分（OR=2.509, 95% CI为1.083~5.814）以及患者欠佳的全身健康状态（OR=5.019, 95% CI为1.294~19.472）是导致术后感染的相关危险因素。在二变量检验中,抗生素使用天数与术后感染具有相关性（P<0.05）。结论骨折的严重程度和患者欠佳的身体健康状态是下颌骨骨折术后感染的危险因素。

关键词: 下颌骨, 骨折, 坚固内固定, 感染, 危险因素

Abstract: To explore risk factors associated with postoperative inflammatory complications(POIC) after rigid internal fixation of mandibular fractures. METHODS: A case-control study was designed and a sample of 447 patients treated with rigid internal fixation for mandibular fractures were selected from January 2009 to December 2015.26 patients developed POIC after treatment were categorized into the experimental group. Twenty-six cases with no complications were enrolled into the control group. Data were collected and bivariate and multiple logistic analyses were used to identify factors associated with POIC between the two groups by SAS9.2 software package. RESULTS: In multiple regression model, an increasing Mandibular Injury Severity Score (OR=2.509; 95%CI 1.083-5.814) and health condition below the baseline (OR=5.019; 95%CI 1.294-19.472) were significantly (P<0.05) associated with an increased risk for a POIC. However, in bivariate analyses, the use of antibiotics was associated with POIC (P<0.05). CONCLUSIONS: Postoperative inflammatory complications are associated with the Mandibular Injury Severity and health condition of the patients.

Key words: Mandible, Fracture, Rigid internal fixation, Infection, Risk factors

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