Shanghai Journal of Stomatology ›› 2015, Vol. 24 ›› Issue (1): 37-40.

• Basic Study • Previous Articles     Next Articles

Establishment of animal model with peri-implantitis after immediate implantation in rabbits

SHEN Lan-Hua,MENG Ling-Na,WANG Xin,JIANG Hui,WANG Shan-Shan   

  1. Department of Stomatology, Nangang Branch, Heilongjiang Provincial Hospital. Haerbin 150001, Heilongjiang Province, China
  • Received:2014-05-15 Online:2015-02-20 Published:2015-07-24
  • Supported by:
    Research Program from the Health Department of Heilongjiang Province (2010-453)

Abstract: PURPOSE: To establish animal model with peri-implantitis after immediate implantation and study bone defect characteristics by Micro-CT. METHODS: Implants were immediately planted in the first mandibular anterior tooth of 12 rabbits. Silk ligatures were placed around one side of the implants to induce peri-implantitis. Micro-CT was used to evaluate bone defect at different periods after implantation. RESULTS: Silk ligatures around the implants were effective to induce peri-implantitis. With the development of peri-implantitis, implants can not be well integrated with bone. Bone defect was gradually produced and then aggravated, and finally formed typical "V-type" bone defect. CONCLUSIONS: The establishment of animal model with peri-implantitis is simple and effective, which provides important references for relative studies in the field of peri-implantitis.

Key words: Peri-implantitis, Immediate implantation, Animal model, Rabbit

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