双极电凝联合1%聚桂醇泡沫硬化剂治疗16例舌微囊型淋巴管畸形疗效观察

doi:10.19439/j.sjos.2021.04.021

上海口腔医学 ›› 2021, Vol. 30 ›› Issue (4): 444-448.doi: 10.19439/j.sjos.2021.04.021

• 论著 • 上一篇

双极电凝联合1%聚桂醇泡沫硬化剂治疗16例舌微囊型淋巴管畸形疗效观察

李嘉朋, 张国润, 陈巨峰, 李金, 刘士维, 贺先明, 冼淡

佛山市第一人民医院口腔医学中心, 广东佛山 528000

收稿日期:2021-04-12 修回日期:2021-07-12 出版日期:2021-08-25 发布日期:2021-09-23
通讯作者: 冼淡,E-mail:xdan@fsyyy.com
作者简介:李嘉朋（1975-）,男,硕士,副主任医师,E-mail:18038862068@189.cn

Evaluation of the effectiveness of treatment of 16 patients with tongue microcystic lymphatic malformation using bipolar coagulation forceps combined with 1% lauromacrogol foam sclerotherapy

LI Jia-peng, ZHANG Guo-run, CHEN Ju-feng, LI Jin, LIU Shi-wei, HE Xian-ming, XIAN Dan

Center of Stomatology, First People's Hospital of Foshan. Foshan 528000, Guangdong Province, China

Received:2021-04-12 Revised:2021-07-12 Online:2021-08-25 Published:2021-09-23

摘要/Abstract

摘要： 目的: 评价双极电凝联合1%聚桂醇泡沫硬化剂治疗舌微囊型淋巴管畸形的临床疗效及安全性。方法: 回顾分析2017年4月—2020年4月佛山市第一人民医院口腔科收治的16例舌微囊型淋巴管畸形患者的临床资料,男7例,女9例,年龄15个月~21岁,平均（8.32±1.21）岁,对治疗效果和并发症进行分析。结果: 16例患者全部随访6~12个月。疗效评价为Ⅳ级11 例（68.75%）,Ⅲ级3例（18.75%）,Ⅱ级2例（12.5%）,Ⅰ级0例,有效率87.5%。1例出现舌黏膜、舌肌坏死。结论: 双极电凝联合1%聚桂醇泡沫硬化剂治疗舌微囊型淋巴管畸形是一种微创、安全、有效的治疗方法。

关键词: 舌, 微囊型淋巴管畸形, 双极电凝, 聚桂醇泡沫硬化剂

Abstract: PURPOSE: To investigate the clinical efficacy and safety of bipolar coagulation forceps combined with 1% lauromacrogol foam sclerotherapy in the treatment of microcystic lymphatic malformation of tongue. METHODS: The clinical data of 16 patients with microcystic lymphatic malformation of the tongue admitted to the Department of Stomatology of Foshan First People's Hospital from April 2017 to April 2020 were retrospectively analyzed, including 7 males and 9 females, aging from 15 months to 21 years. The average age of patients was 8.32±1.21 years. The efficacy and complications of the patients were evaluated. RESULTS: All 16 patients were followed up for 6 to 12 months. The clinical response was evaluated as eleven patients (68.75%) for grade Ⅳ, three (18.75%) for grade Ⅲ, two (12.5%) for grade Ⅱ, and the effective rate was 87.5%. Necrosis of tongue mucosa and muscle occurred in 1 patient. CONCLUSIONS: Bipolar coagulation forceps combined with 1% lauromacrogol foam sclerotherapy is a minimally invasive, safe and effective treatment for tongue microcystic lymphatic malformation.

Key words: Tongue, Microcystic lymphatic malformation, Bipolar coagulation forceps, Lauromacrogol foam sclerotherapy

中图分类号:

R782.2

李嘉朋, 张国润, 陈巨峰, 李金, 刘士维, 贺先明, 冼淡. 双极电凝联合1%聚桂醇泡沫硬化剂治疗16例舌微囊型淋巴管畸形疗效观察[J]. 上海口腔医学, 2021, 30(4): 444-448.

LI Jia-peng, ZHANG Guo-run, CHEN Ju-feng, LI Jin, LIU Shi-wei, HE Xian-ming, XIAN Dan. Evaluation of the effectiveness of treatment of 16 patients with tongue microcystic lymphatic malformation using bipolar coagulation forceps combined with 1% lauromacrogol foam sclerotherapy[J]. Shanghai Journal of Stomatology, 2021, 30(4): 444-448.

参考文献

[1] 中华医学会整形外科分会血管瘤和脉管畸形学组. 血管瘤和脉管畸形的诊断及治疗指南(2019版)[J]. 组织工程与重建外科杂志, 2019, 15(5): 277-317.
[2] Wiegand S, Eivazi B, Zimmermann AP, et al.Microcystic lymphatic malformations of the tongue: diagnosis, classification, and treatment[J]. Arch Otolaryngol Head Neck Surg, 2009, 135(10): 976-983.
[3] Upadhyaya VD, Bhatnagar A, Kumar B, et al.Is multiple session of intralesional bleomycin mandatory for complete resolution of macrocystic lymphatic malformation?[J]. Indian J Plast Surg, 2018, 51(1): 60-65.
[4] Gu A, Bauman NM.Bipolar radiofrequency ablation (Coblation) of external auditory canal lymphatic malformation and other soft stenoses[J]. Ann Otol Rhinol Laryngol, 2017, 126(12): 835-838.
[5] Strychowsky JE, Rahbar R, O′Hare MJ, et al. Sirolimus as treatment for 19 patients with refractory cervicofacial lymphatic malformation[J]. Laryngoscope, 2018, 128(1): 269-276.
[6] Parashar G, Shankar G, Sahadev R, et al.Intralesional sclerotherapy with bleomycin in lymphatic malformation of tongue an institutional experience and outcomes[J]. J Indian Assoc Pediatr Surg, 2020, 25(2): 80-84.
[7] Rosen RJ, Nassiri N, Drury JE.Interventional management of high-flow vascular malformations[J]. Tech Vasc Interv Radiol, 2013, 16(1): 22-38.
[8] Achauer BM, Chang CJ, Vander Kam VM.Management of hemangioma of infancy: review of 245 patients[J]. Plast Reconstr Surg, 1997, 99(5): 1301-1308.
[9] Renton JP, Smith RJ.Current treatment paradigms in the management of lymphatic malformations[J]. Laryngoscope, 2011, 121(1): 56-59.
[10] 李克雷, 王玉平, 陈涛, 等. 舌微囊型淋巴管畸形分型及疗效的回顾性分析[J]. 中华口腔医学杂志, 2019, 54(5): 303-308.
[11] Anggreyni G, Agustriani N, Agustriani N, et al.Comparison of different therapeutic approaches for children with common lymphatic malformation[J]. Med J Malaysia, 2020, 75(Suppl 1): 32-36.
[12] 杨耀武, 郑家伟, 孙沫逸, 等. 聚桂醇硬化剂治疗口腔颌面部血管瘤和脉管畸形专家共识[J].中国口腔颌面外科杂志, 2018, 16(3): 275-278.
[13] Chai Y, Zhou Z, Song J, et al.Safety of intralesional injection of lauromacrogol combined with triamcinolone for infantile hemangiomas[J]. J Dermatol, 2019, 46(9): 770-776.
[14] Kulungowski AM, Patel M.Lymphatic malformations[J]. Semin Pediatr Surg, 2020, 29(5): 150971.
[15] Mai HM, Zheng JW, Zhou Q, et al.Intralesional injection of pingyangmycin is a safe and effective treatment for microcystic lymphatic malformations in the tongue[J]. Phlebology, 2013, 28(3): 147-152.
[16] 张世文, 安常明, 黄仁超, 等. 采用直型双极电凝镊进行全程精细化解剖在甲状腺外科手术中的应用[J].中华耳鼻咽喉头颈外科杂志, 2020, 55(2): 139-143.
[17] 黄星星, 邹海啸, 郭小科, 等. 手术切除联合硬化剂治疗巨大舌静脉畸形[J].中华整形外科杂志, 2016, 32(1): 14-17.
[18] 王亮, 吴长华, 宋丹, 等. 聚多卡醇泡沫硬化剂联合平阳霉素在学龄前儿童静脉畸形治疗中的应用[J].组织工程与重建外科杂志, 2020, 16(3): 182-185.
[19] 杨希,林晓曦.脉管畸形的治疗策略及风险评估[J].皮肤科学通报, 2018, 35(5): 568-575.

双极电凝联合1%聚桂醇泡沫硬化剂治疗16例舌微囊型淋巴管畸形疗效观察

Evaluation of the effectiveness of treatment of 16 patients with tongue microcystic lymphatic malformation using bipolar coagulation forceps combined with 1% lauromacrogol foam sclerotherapy

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