上海口腔医学 ›› 2017, Vol. 26 ›› Issue (5): 516-520.doi: 10.19439/j.sjos.2017.05.010

• 论著 • 上一篇    下一篇

中国口腔癌症患者生活质量量表的编制与评测

杨艳杰, 秦帅华, 李文鹿   

  1. 郑州大学第一附属医院 口腔科,河南 郑州 450052
  • 收稿日期:2017-01-05 修回日期:2017-05-25 出版日期:2017-10-25 发布日期:2017-11-23
  • 通讯作者: 李文鹿,E-mail: lwldoctor@163.com
  • 基金资助:
    国家自然科学基金(81402578) [作者简介] 杨艳杰(1985-),女,硕士,E-mail:yangyanjiedoctor@163.com

Development of a quality of life instrument for evaluation of the quality of life scale for Chinese patients with oral cancer

YANG Yan-jie, QIN Shuai-hua, LI Wen-lu   

  1. Department of Stomatology, the First Affiliated Hospital of Zhengzhou University. Zhengzhou 450052, Henan Province, China
  • Received:2017-01-05 Revised:2017-05-25 Online:2017-10-25 Published:2017-11-23

摘要: 目的编制适合中国口腔癌患者的生活质量量表, 并验证该量表信度和效度。方法参照简明健康状况调查问卷(SF-36)和华盛顿大学头颈肿瘤生活质量量表(UW-QOL),并结合中国人群社会文化特点,编制郑州大学口腔癌患者生活质量量表(Zhengzhou University Oral Cancer-QOL,ZZU-QOL)。对271例患者进行调查后,采用SPSS19.0软件包中的t检验、相关分析、因子分析等方法对测试版量表信度和效度进行评价。结果在重测信度方面,各领域和整个量表在2次测量之间的相关系数为0.86~1.00,均无显著差异。在同质信度方面,各个领域的Cronbach系数均大于0.6,显示测试版量表具有较好的信度。在结构效度方面ZZU-QOL、SF-36和UW-QOL量表经因子分析选出的前7个因子方差累计贡献率分别为69.3%、63.4%和66.5%。以SF-36和UW-QOL作为效标,其效标效果分别为0.768和0.634。ZZU-QOL量表能敏感地区分口腔癌患者术前与术后生活质量的差异。结论ZZU-QOL具有较好的信度和效度,适用于中国口腔癌患者生活质量的测评。

关键词: 口腔癌, 生活质量, 测量量表

Abstract: PURPOSE: To develop a quality of life instrument for Chinese patients with oral cancer and to assess its reliability, validity and sensitivity. METHODS: A 44-item QOL questionnaire was developed with reference to the 36-item medical outcomes study on short-form health status (SF-36) and University of Washington Quality of Life Questionnaire (UW-QOL), combining with China's population and socio-cultural characteristics, named as Zhengzhou university oral cancer quality of life (ZZU-QOL) scale. Based on 271 patients, student's t test, correlation analysis, factor analysis were performed for its reliability and validity using SPSS 19.0 software package. RESULTS: Test-retest reliability: in all areas and for total score between 2 measurements of the correlation coefficient in the range of 0.86-1.00, there was no significant difference. Homogeneity reliability: Cornbrash'a coefficient in all fields was larger than 0.6, indicating the scale had good reliability. Construct validity: ZZU-QOL, SF-36 analysis and UW-QOL scale factor selected by the first seven cumulative contribution factor variance were 69.3%, 63.4% and 66.5%. The criterion validity with SF-36 and UW-QOL was 0.768 and 0.634, respectively. The ZZU-QOL scale can sensitively distinguish differences in preoperative and postoperative quality of life of oral cancer. CONCLUSIONS: The ZZU-QOL scale is practical, reliable and valid, and might be used for measuring the quality of life in Chinese patients with oral cancer.

Key words: Oral cancer, Quality of life, Instrument evaluation

中图分类号: