Shanghai Journal of Stomatology ›› 2015, Vol. 24 ›› Issue (1): 124-128.

• Review Article • Previous Articles    

Research progress of quantitative DNA analysis in oral carcinoma and precancerous lesions

XIAO Xuan,SHI Lin-Jun,ZHOU Zeng-tong   

  1. Department of Oral Mucosal Diseases, Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine;Shanghai Key Laboratory of Stomatology. Shanghai 200011, China
  • Received:2013-11-11 Online:2015-02-20 Published:2015-07-24
  • Supported by:
    Research Fund of Science and Technology Committee of Shanghai Municipality (11DZ1972600) and Research Fund of Bureau of Health of Shanghai Municipality (ZYSNXD-CC-ZDYJ004)

Abstract: Normal individual cells had 23 pairs of chromosome and stable DNA content. DNA content was varied during malignant transformation, which was specific feature of tumor. Quantitative DNA analysis can reflect cellular physiological or pathological condition by nuclear DNA content, which had significant role in early diagnosis, predication of prognosis and treatment selection. This article summarized the research progress of quantitative DNA analysis in oral carcinoma and precancerous lesions in recent years.

Key words: Quantitative DNA analysis, DNA ploidy, Oral carcinoma, Precancerous lesions

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