Abstract: PURPOSE: To observe the effect of anti-gingivitis IgY toothpaste in control of gingivitis and plaque. METHODS: The study was a double-blind, randomized, parallel-controlled clinical trail with a total of 100 subjects who were divided into two groups, experimental group and control group. The subjects in experimental group used anti-gingivitis IgY toothpaste to brush twice daily for 3 minutes, and the subjects in control group used none anti-gingivitis IgY toothpaste. The examiner recorded GI, PI and BOP index of all subjects at the baseline, 6-weeks and 12-weeks. SPSS21.0 software package was used for statistical analysis. RESULTS: Twelve weeks later, there were significant differences in GI and BOP between the two groups. Yet no significant difference was found in PI. CONCLUSIONS: Anti-gingivitis IgY toothpaste is effective in control of gingivitis.

Key words: Gingivitis, IgY toothpaste, Clinical trail