Fibre-type differences in masseter muscle of Beagle dogs with implanted functional appliance therapy

Abstract

Abstract: PURPOSE: To observe the changes of MyHC-I expression in masseter muscle of Beagle dogs with implanted functional appliance therapy，and to investigate the adaptive remodeling of masticatory muscle. METHODS： Eight, seven-month-old, male Beagle dogs were randomly assigned to experimental group and control group and were killed at 4,8,12 weeks during treatment and 4 weeks after the appliance removed(16 weeks). Serial cross-sections of superficial masseter muscle were cut and stained with MyHC-I antibodies.SPSS11.5 software package was used for statistical analysis. RESULTS: The positive expression rate of MyHC-I was 7.61% in the control group, and 20.43% in the experimental groups at 4 weeks﹙P<0.01﹚. The amount of type I fibres reached to peak at 8 weeks. With increase of treatment time, the amount of type I fibres gradually reduced. At 16 weeks, the amount of type I fibres was similar to the control groups. CONCLUSIONS: The expression of MyHC-I is significantly changed in masseter muscles of Beagle dogs with implanted functional appliance therapy. Implanted functional appliance forward mandibular displacement therapy can obviously promote the adaptive remodeling of masticatory muscle.

Key words: Implant, Functional appliance, Masseter muscle

CLC Number:

R873.5

SUN Xu-rong, LIN Xin-ping.. Fibre-type differences in masseter muscle of Beagle dogs with implanted functional appliance therapy[J]. Shanghai Journal of Stomatology, 2016, 25(1): 22-26.

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