The value of ultrasonic elastography in diagnosis of salivary gland lesions in patients with Sjögren's syndrome

doi:10.19439/j.sjos.2018.01.017

Abstract

Abstract: PURPOSE: To evaluate the value of strain rate ratio (SR) and acoustic radiation force impulse (ARFI) imaging in the diagnosis of salivary glands lesions in patients with Sjögren's syndrome (SS). METHODS: Thirty-six outpatients with SS in the Department of Oral Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine from January 2017 to July 2017 were collected. All patients were diagnosed as SS according to American-European Consensus Group criteria of 2002. 25 healthy controls were chosen as control. The bilateral parotid gland and submandibular gland were examined by strain rate ratio and ARFI imaging, and the SR and shear wave velocity (SWV) value were obtained. The differences in SR or SWV values between the left and right sides of the parotid gland or submandibular gland and between SS group and healthy control group were analyzed using SPSS 22.0 software package. RESULTS: There was no significant difference in SR and SWV value between left and right parotid gland and submandibular gland in the SS group and the healthy control group (P>0.05). There were significant differences in SR values between bilateral parotid gland and submandibular gland (P<0.05).There was significant difference in SWV values between the two groups (P<0.05). With 0.8962 as the cutoff value, the sensitivity of SS diagnosis in the parotid gland was 77.8% by using SR, the specificity was 88.0% and the area under the curve was 0.844. With 0.8987 as the cutoff value, the sensitivity of SS diagnosis in the submandibular gland was 47.22%,the specificity was 84.0% and the area under the curve was 0.652. By using ARFI technique, the sensitivity of SS diagnosis in the parotid gland was 91.7%, the specificity was 88.0%, and the area under the curve was 0.943, when the cutoff value was 1.6288. With 1.8788 as the cutoff value, the sensitivity of SS diagnosis in the submandibular gland was 44.4%, the specificity was 96.0%, and the area under the curve was 0.614. CONCLUSIONS: SR and ARFI imaging method can provide SR and SWV value of salivary gland to quantify the hardness of salivary glands in SS, which has great value in diagnosis of SS.

Key words: Sj?gren's syndrome, Parotid gland, Submandibular gland, Ultrasonic elastic strain rate ratio method, Acoustic radiation force impulse

CLC Number:

R445.1

ZHANG Wei-qian, GONG Xia, XIONG Ping. The value of ultrasonic elastography in diagnosis of salivary gland lesions in patients with Sjögren's syndrome[J]. Shanghai Journal of Stomatology, 2018, 27(1): 73-78.

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