Shanghai Journal of Stomatology ›› 2016, Vol. 25 ›› Issue (3): 281-283.

• Original Articles • Previous Articles     Next Articles

Establishment of traumatic occlusion model in Sprague-Dawley rats

XIN Xian-zhen1, YANG Xu1, WEI Bin2   

  1. 1. Department of Prosthodontics;
    2. Department of Stomatology Special Consultation Clinic, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine Shanghai Key Laboratory of Stomatology. Shanghai 200011, China
  • Received:2015-07-01 Revised:2015-09-21 Online:2016-06-25 Published:2016-07-22

Abstract: PURPOSE: In this study, different methods were used to observe and obtain the most effective one to establish occlusal trauma model in Sprague-Dawley rats. METHODS: SPF male SD rats weighing 150~200 g and aged 10 to 12 weeks were used in this study. The rats' maxillary molars were bonded with stainless steel wire, resin , casting half crown , casting half combined crowns, half crown using selective laser melting (SLM) technology, half combined crowns using SLM technology through Super-bond and Multi-link bonding under general anesthesia. After bonding, the experimental device expulsion rates were observed daily. The data was analyzed statistically using Fisher's exact test with SAS 8.2 software package. RESULTS: There was no significant difference between the falling rates of using super-bond and using multi-link. Under the situation in which different bonding methods exerted no influence on the falling rates, there was significant difference between different experimental devices (P<0.0001). CONCLUSIONS: The restorations fabricated with SLM technology is valid and feasible to induce occlusal point in building occlusal trama model using SD rats.

Key words: Traumatic occlusion, SD rats, Experimental model

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