Abstract: PURPOSE: To investigate the clinical efficacy and effects of CAD/CAM zirconia all-ceramic crown, cobalt-chromium alloy and silver-palladium alloy porcelain-fused-to-metal crown restorations on periodontal tissues. METHODS: Forty-nine teeth with crowns in 46 patients were randomly assigned into CAD/CAM zirconia all-ceramic crown group, cobalt-chromium alloy porcelain-fused-to-metal crown group and silver-palladium alloy porcelain-fused-to-metal crown group. The amounts of GCF, TNF-α and IL-6 were analyzed before and 12 months after restorations, and the clinical efficacy was evaluated. RESULTS: Comparing the clinical efficacy within 3 groups, indicators such as color match and the status of gums in CAD/CAM zirconia all-ceramic crown group were significantly better than other 2 groups (P<0.05). The amounts of GCF, TNF-α and IL-6 in CAD/CAM zirconia all-ceramic crown group were also significantly better than other 2 groups (P<0.01). CONCLUSIONS: CAD/CAM zirconia all-ceramic crown restoration had better clinical efficacy than cobalt-chromium alloy and silver-palladium alloy porcelain-fused-to-metal crown restorations with no apparently damage to periodontal tissues.

Key words: CAD/CAM technique, Zirconia all-ceramic crown, Periodontal tissue, TNF-α, IL-6