氯己定预处理牙本质后对自酸蚀粘接剂粘结效果的影响

doi:10.19439/j.sjos.2020.02.008

上海口腔医学 ›› 2020, Vol. 29 ›› Issue (2): 150-154.doi: 10.19439/j.sjos.2020.02.008

氯己定预处理牙本质后对自酸蚀粘接剂粘结效果的影响

荆得宝¹, 王丽琴², 胡玉凤², 朱静²

1.上海市浦东新区公利医院口腔科,上海 200135;
2.上海市口腔病防治院分院口腔内科,上海 200031

收稿日期:2019-07-15 修回日期:2019-09-01 出版日期:2020-04-25 发布日期:2020-04-30
通讯作者: 王丽琴,E-mail:caiju_donglixia@163.com
作者简介:荆得宝(1975-),男,副主任医师,硕士,E-mail:jing_debao@163.com
基金资助:
上海市卫生和计划生育委员会科研项目(201640289)

Effect of chlorhexidine on the bonding effect of self-acid adhesive to pre-treatment dentin

JING De-bao¹, WANG Li-qin², HU Yu-feng², ZHU Jing²

1.Department of Stomatology, Gongli Hospital, Shanghai Pudong New Area.Shanghai 200135;
2.Department of Oral Medicine, Shanghai Stomatological Disease Center. Shanghai 200031, China

Received:2019-07-15 Revised:2019-09-01 Online:2020-04-25 Published:2020-04-30

摘要/Abstract

摘要： 目的评价2%氯己定在不同作用时间下对自酸蚀粘接剂稳定性的影响。方法选择50颗无龋离体牙作为研究对象,制作牙本质试件,采用Adper^TM Easy One自酸蚀粘接剂粘结,堆积复合树脂,制作粘结试件。试件分别用2%氯己定进行0、15、30、45、60 s预处理,分别在老化循环前后进行微拉伸强度和扫描电镜测试,检测氯己定对自酸蚀粘结的影响。采用SPSS 19.0软件包对数据进行统计学分析。结果氯己定预处理45、60 s组即刻测试微拉伸强度显著高于对照组,老化循环后氯己定预处理60 s组微拉伸强度较对照组高,差异显著(P<0.05)。结论 2%氯己定能提高自酸蚀粘接剂的粘结强度,改善粘结界面的老化退变,提高粘结的持久性。

关键词: 氯己定, 自酸蚀粘结, 微拉伸强度

Abstract: PURPOSE: To evaluate the effect of 2% chlorhexidine(CHX) on the self-etching adhesive to dentin. METHODS: Fifty carious free molars were selected to expose the flat dentin surface. The specimens were bonded with composite resin by self-etching adhesive,which were pretreated by 2% CHX for 0, 15, 30, 45 and 60 s. The microtensile bond strength (μTBS) and scanning electron microscope(SEM) were evaluated before and after thermocycling. SPSS 19.0 software package was used for statistical analysis. RESULTS: μTBS of the 45 and 60s-CHX pretreated group had significant difference before thermocycling, significantly higher than the control group(P<0.05). The 60s-CHX pretreated group showed significant greater μTBS than the control group after thermocycling(P<0.05). CONCLUSIONS: 2%CHX pretreatment can improve the bonding strength of the self-etching adhesive, and slow down the aging progress of bonding interface.

Key words: Chlorhexidine, Self-etching adhesive, Microtensile bond strength

中图分类号:

R781.3

荆得宝, 王丽琴, 胡玉凤, 朱静. 氯己定预处理牙本质后对自酸蚀粘接剂粘结效果的影响[J]. 上海口腔医学, 2020, 29(2): 150-154.

JING De-bao, WANG Li-qin, HU Yu-feng, ZHU Jing. Effect of chlorhexidine on the bonding effect of self-acid adhesive to pre-treatment dentin[J]. Shanghai Journal of Stomatology, 2020, 29(2): 150-154.

参考文献

[1] Van Meerbeek B, Perdigão J, Lambrechts P, et al.The clinical performance of adhesives[J]. J Dent, 1998, 26(1): 1-20.
[2] Betancourt DE, Baldion PA, Castellanos JE.Resin-dentin bonding interface: mechanisms of degradation and strategies for stabilization of the hybrid layer[J]. Int J Biomater, 2019: 5268342.
[3] Tjaderhane L, Larjava H, Sorsa T, et al.The activation and function of host matrix metalloproteinases in dentin matrix breakdown in caries lesions[J]. J Dent Res, 1998, 77(8): 1622-1629.
[4] Feitosa VP, Sauro S, Zenobi W, et al.Degradation of adhesive-dentin interfaces created using different bonding strategies after five-year simulated pulpal pressure[J]. J Adhes Dent,2019, 21(3): 199-207.
[5] Tjaderhane L.Dentin bonding: can we make it last?[J]. Oper Dent, 2015, 40(1): 4-18.
[6] Zhou W, Liu SY, Zhou XD, et al.Modifying adhesive materials to improve the longevity of resinous restorations[J]. Int J Mol Sci,2019, 20(3): 723-742.
[7] Varoni E, Tarce M, Lodi G, et al.chlorhexidine(CHX) in dentistry: state of the are[J]. Minerva Stomatol, 2012, 61(9): 399-341.
[8] Gendron R, Grenier D, Sorsa T, et al.Inhibition of the activities of matrixmetalloproteinases 2, 8, and 9 by chlorhexidine[J]. Clin Diagn Lab Immunol, 1999, 6(3): 437-439.
[9] Hebling J, Pashley DH, Tjaderhane L, et al.Chlorhexidine arrests subclinical degradation of dentin hybrid layers in vivo[J]. J Dent Res,2005, 84(8): 741-746.
[10] Sulkala M, Tervahartiala T, Sorsa T, et al.Tjaderhane L. Matrixmetalloproteinase-8 (MMP-8) is the major collagenase in human dentin[J]. Arch Oral Biol, 2007, 52(2): 121-127.
[11] Mazzoni A, Pashley D, Tay FR, et al.Immunohistochemical identificationof MMP-2 and MMP-9 in human dentin: correlative FEI-SEM/TEM analysis[J]. J Biomed Mater Res A, 2009, 88(3): 697-703.
[12] Santos J, Carrilho M, Tervahartiala T, et al.Determination of matrix metalloproteinases in human radicular dentin[J]. J Endod,2009,35(5): 686-689.
[13] Xu H, Snider TN, Wimer HF, et al. Multiple essential MT1-MMP functions in tooth root formation, dentinogenesis,tooth eruption [J]. Matrix Biol, 2016, 52-54: 266-283.
[14] Mazzoni A, Maravic T, Tezvergil-Mutluay A, et al.Biochemical and immunohistochemical identification of MMP-7 in human dentin[J]. J Dent,2018, 79: 90-95.
[15] Frassetto A, Breschi L, Turco G, et al.Mechanisms of degradation of the hybrid layer in adhesive dentistry and therapeutic agents to improve bond durability-A literature review[J]. Dent Mater, 2016, 32(2): E41-E53.
[16] Fiorillo L.Chlorhexidine gel use in the oral district: a systematic review[J]. Gels, 2019, 5(2): 31-47.
[17] Mohammadi Z, Jafarzadeh H, Shalavi S, et al.Antimicrobial efficacy of chlorhexidine as a root canal irrigant: a literature review[J]. J Oral Sci, 2014, 56(2): 99-103.
[18] Araújo MS, Souza LC, Apolonio FM, et al.Two-year clinical evaluation of chlorhexidine incorporation in two-step self-etch adhesive[J]. J Dent, 2015, 43(1): 140-148.
[19] Suma N, Shashibhushan K, Subba Reddy VV.Effect of dentin disinfection with 2% chlorhexidine gluconate and 0.3% iodine on dentin bond strength: an in vitro study[J]. Int J Clin Pediatr Dent, 2017,10(3): 223-228.
[20] Gajjela RS, Satish RK, Sajjan GS, et al.Comparative evaluation of chlorhexidine, grape seed extract, riboflavin/chitosan modification on microtensile bond strength of composite resin to dentin after polymerase chain reaction thermocycling: An in vitro study[J]. J Conserv Dent, 2017, 20(2): 120-124.
[21] Pinheiro SL, Pereira DR, De Milito F, et al.Influence of metalloproteinases on dentin hybridization of one-bottle or self-etch dental bonding systems[J]. J Contemp Dent Pract, 2014, 15(6): 705-711.
[22] Rayar S, Sadasiva K, Singh P, et al.Effect of 2% chlorhexidine on resin bond strength and mode of failure using two different adhesives on dentin: an in vitro study[J]. J Pharm Bioallied Sci, 2019, 11(Suppl 2): S325-S330.

氯己定预处理牙本质后对自酸蚀粘接剂粘结效果的影响

Effect of chlorhexidine on the bonding effect of self-acid adhesive to pre-treatment dentin

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 6

编辑推荐

Metrics

本文评价

[1]	刘慧楠, 张富华, 蒲灼光. 不同荡洗策略治疗有瘘型慢性根尖周炎的临床效果比较[J]. 上海口腔医学, 2023, 32(2): 188-192.
[2]	谢惠兰, 陈江, 曹白雨, 林毅. 负载氯己定的埃洛石纳米管对牙本质粘结强度的影响[J]. 上海口腔医学, 2022, 31(5): 471-475.
[3]	程刚, 王留宏, 杨惠, 娄新田, 王一霖. 氯己定联合机械清创对种植体周围炎的治疗效果及对患者SF-36评分的影响[J]. 上海口腔医学, 2020, 29(4): 400-404.
[4]	潘秋华, 黄大维, 王青泰. 止血剂对乳牙牙本质黏结强度的影响[J]. 上海口腔医学, 2017, 26(2): 184-187.
[5]	赵聪, 迟爽, 李彤, 李贺, 李天博, 张志民. MMPs抑制剂对湿性黏结微渗漏的影响[J]. 上海口腔医学, 2016, 25(5): 548-552.
[6]	宋雪莲, 孙莹莹, 刘扬, 陈青, 毕欣欣, 于静涛. 羧甲基壳聚糖及其复合物对根管内粪肠球菌的作用评价[J]. 上海口腔医学, 2013, 22(3): 265-269.