上海口腔医学

上海口腔医学 ›› 2022, Vol. 31 ›› Issue (3): 330-336.doi: 10.19439/j.sjos.2022.03.022

• 系统评价 • 上一篇    

心理干预对头颈部恶性肿瘤患者负性情绪及生活质量影响的meta分析

夏佳琳1,2, 曾奕玮3, 赵小妹2,*, 侯黎莉2,*   

  1. 1.成都中医药大学 护理学院,四川 成都 610075;
    2.上海交通大学医学院附属第九人民医院 护理部,上海 200011;
    3.成都中医药大学 针灸推拿学院,四川 成都 610075
  • 收稿日期:2021-06-25 修回日期:2021-08-02 出版日期:2022-06-25 发布日期:2022-07-07
  • 通讯作者: 侯黎莉,E-mail：pisces_liz@163.com; 赵小妹,E-mail：Zhxm58327107@126.com。*共同通信作者
  • 作者简介:夏佳琳（1994-）,女,在读硕士研究生,E-mail：jialin_xia@outlook.com
  • 基金资助:
    上海交通大学医学院护理学科建设项目

Psychological intervention for negative emotion and quality of life of patients with head and neck cancer (HNC): a meta-analysis

XIA Jia-lin1,2, ZENG Yi-wei3, ZHAO Xiao-mei2, HOU Li-li2   

  1. 1. School of Nursing, Chengdu University of Traditional Chinese Medicine. Chengdu 610075, Sichuan Province;
    2. Department of Nursing, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine. Shanghai 200011;
    3. School of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine. Chengdu 610075, Sichuan Province, China
  • Received:2021-06-25 Revised:2021-08-02 Online:2022-06-25 Published:2022-07-07

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摘要： 目的: 系统分析和评价心理干预对头颈部恶性肿瘤(HNC)患者负性情绪及生活质量的影响,为开展HNC心理干预提供依据。方法: 计算机检索PubMed、Central、Embase、clinicaltrials.gov、ICTRP、Web of Science、CBM、CNKI、VIP、万方等网站有关HNC患者心理干预的随机对照临床试验(RCT)。检索时间从数据库建立到2021年5月15日,经过筛选、质量评价和数据提取,采用RevMan 5.4软件进行meta分析。结果: 最终纳入RCT 18项,包括2 097例受试者。与对照组常规护理相比,试验组加入心理干预降低了HNC患者的焦虑评分[SMD=-2.33,95%CI（-2.96,-1.70）,P<0.000 01]、抑郁评分[SMD=-2.26,95%CI（-2.78,-1.74）,P<0.000 01],生活质量评分提高[SMD=6.04,95%CI（1.53,10.56）,P=0.009]及症状自评量表评分[MD=29.99,95%CI（-36.22,-23.76）,P<0.000 01]提高。结论: 心理干预能有效缓解HNC患者的焦虑、抑郁情绪,促进HNC患者的心理健康和生活质量。但受纳入RCT质量的限制,需要更多设计严谨、方法学质量较高的研究进行验证。

关键词: 心理干预, 头颈部恶性肿瘤, 负性情绪, 生活质量, Meta分析

Abstract: PURPOSE: To systematically assess the efficacy of psychological intervention for patients with head and neck cancer (HNC) in easing negative emotion and improving quality of life, so as to provide evidence-based reference for clinical psycho-intervention of HNC patients. METHODS: PubMed, Central, Embase, clinicaltrials.gov, ICTRP, Web of science, CBM, CNKI, VIP, and Wan Fang database were searched from inception to 15th, May for randomized controlled trails conducted to assess psychological intervention for HNC patients. The retrieval, screening, quality evaluation, and data extraction were elaborately proceeded by two reviewers independently. Meta analysis was performed using RevMan 5.4 software. RESULTS: Eighteen RCTs were included with 2 097 participants. Meta analysis showed that compared to control group, psychological intervention group manifested greater decrease in anxiety scores [SMD=-2.33, 95%CI（-2.96,-1.70）, P<0.000 01] and depression scores [SMD=-2.26, 95%CI（-2.78,-1.74）, P<0.000 01], and better increase in QOL scores [SMD=6.04, 95%CI（1.53,10.56）, P=0.009] and SQL-90 scores [MD=29.99, 95%CI（-36.22, -23.76）,P<0.000 01]. CONCLUSIONS: The anxiety and depression of HNC patients can be effectively relieved through psychological intervention, so that their quality of life and metal health status can be improved. Due to the limitation of quality of included RCT , the result remains to be further validated by more well-designed and better-qualified study.

Key words: Psychological intervention, Head and neck cancer, Negative emotion, Quality of life, Meta analysis

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