上海口腔医学

上海口腔医学 ›› 2019, Vol. 28 ›› Issue (3): 288-292.doi: 10.19439/j.sjos.2019.03.013

• 论著 • 上一篇    下一篇

口腔恶性肿瘤术后患者放疗前营养状况与膳食营养素摄入的相关性研究

张海峰1, 张美芳1, 赵安达1, 李烿烿2   

  1. 1.上海交通大学医学院附属第九人民医院 临床营养科;
    2.放疗科,上海 200011
  • 收稿日期:2019-02-27 修回日期:2019-03-12 出版日期:2019-06-25 发布日期:2019-08-09
  • 通讯作者: 李烿烿,E-mail：rongrli2003@163.com
  • 作者简介:张海峰（1971-）,女,硕士,E-mail：zhanghf1290@sh9hospital.org
  • 基金资助:
    国际注册临床课题（NCT02776124）

Correlation between nutritional status before radiotherapy and dietary intake in patients with oral cancers

ZHANG Hai-feng1, ZHANG Mei-fang1, ZHAO An-da1, LI Rong-rong2   

  1. 1. Department of Clinical Nutrition;
    2.Department of Radiation Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine. Shanghai 200011, China
  • Received:2019-02-27 Revised:2019-03-12 Online:2019-06-25 Published:2019-08-09

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摘要： 目的 探讨口腔恶性肿瘤术后患者放疗前膳食营养素摄入量与主观整体营养状况评量表（PG-SGA）评分间的相关性。方法 选取上海交通大学医学院附属第九人民医院营养门诊就诊的口腔恶性肿瘤术后患者65例,采用72 h膳食调查法了解患者放疗前食物摄入情况,采用PG-SGA对患者的营养状况进行定量评分。采用SPSS 23.0软件包对数据进行统计学分析。结果 男性患者重度营养不良病例数显著高于女性患者（P<0.05）。营养良好/轻度营养不良组、中度营养不良组、重度营养不良组患者膳食提供能量、脂肪量及其供能比、碳水化合物量及其供能比均在中国居民膳食营养素参考摄入量范围内,蛋白质摄入量及其供能比均超过中国居民膳食营养素参考摄入量,3组患者之间无显著差异。营养良好/轻度营养不良组、中度营养不良组、重度营养不良组硒摄入量分别为67.15、81.04、81.59 μg,维生素E分别为27.81、30.88、26.40 mg α-TE,维生素C分别为150.19、159.81、183.71 mg,视黄醇分别为904.65、1401.51、1373.81 μg RAE,均显著高于参考摄入量。烟酸分别为12.97、18.76、14.27 mg NE,达到或高于参考摄入量,3组间无显著差异。在男性患者中,膳食中的能量和烟酸的摄入与PG-SGA得分呈负相关（P<0.05）。结论 口腔恶性肿瘤术后患者放疗前营养不良发生率高,膳食提供能量和蛋白质、脂肪、碳水化合物以及硒、维生素E、维生素C、视黄醇、烟酸等微量营养素的平均摄入量达到或高于参考摄入量。男性患者能量和烟酸的摄入与PG-SGA得分呈负相关。

关键词: 口腔恶性肿瘤, 72 h膳食调查, 膳食营养素, PG-SGA评分

Abstract: PURPOSE: To explore the correlation between dietary nutrient intake and PG-SGA score in patients with oral cancers before radiotherapy. Methods: Sixty-five patients with oral cancers treated in Shanghai Ninth People's Hospital were selected. The 72-hour dietary survey method was used to understand the food intake of the patients. PG-SGA was used to make quantitative scoring of the nutritional status of the patients. SPSS 23.0 software package was used for data analysis. Results: The number of severe malnutrition cases in male patients was significantly higher than that in female patients (P<0.05). Energy, fat and fat energy ratio, carbohydrate and carbohydrate energy ratio from diet in good nutrition/mild malnutrition group, moderate malnutrition, severe malnutrition patients were over reference intake of dietary nutrients for Chinese residents; protein intake and protein energy ratio were greater than reference intake of nutrients for Chinese people. There was no significant difference among the three groups. The selenium intake of the well-nourished/mildly malnourished, moderately malnourished and severely malnourished groups was 67.15, 81.04 and 81.59 μg; vitamin E was 27.81, 30.88, 26.40 mg α-TE; vitamin C was 150.19, 159.81, 183.71 mg; retinol was 904.65, 1401.51, and 1373.81 μg RAE, respectively. Niacin was 12.97, 18.76 and 14.27 mg NE, respectively, reaching or exceeding the reference intake. There was no significant difference among the three groups. In male patients, dietary energy and niacin intake were negatively correlated with PG-SGA score (P<0.05). Conclusions: Patients with oral cancers have a high incidence of malnutrition before radiotherapy, and the average intake of dietary energy, protein, fat, carbohydrates and micronutrients such as selenium, vitamin E, vitamin C, retinol and niacin reached or exceeded the reference intake. Energy and niacin intake were negatively correlated with PG-SGA score in male patients.

Key words: Oral cancers, 72h dietary survey, Dietary nutrients, PG-SGA score

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