氟化钠护齿剂在预防学龄前儿童乳牙龋齿中的疗效观察

doi:10.19439/j.sjos.2019.01.009

上海口腔医学 ›› 2019, Vol. 28 ›› Issue (1): 48-42.doi: 10.19439/j.sjos.2019.01.009

氟化钠护齿剂在预防学龄前儿童乳牙龋齿中的疗效观察

苏红如^1,*, 杨忍忍^2,*, 钱文昊^1#, 余金明^2#

1.上海市徐汇区牙病防治所,上海 200032;
2.复旦大学公共卫生学院,卫生部卫生技术评估重点实验室,国民健康社会风险预警协同创新中心,上海 200032

收稿日期:2018-08-16 修回日期:2018-10-25 出版日期:2019-02-25 发布日期:2019-04-12
通讯作者: 钱文昊,E-mail:pingyanlaoto@hotmail.com;余金明,E-mail:jmy@fudan.edu.cn。^#共同通信作者
作者简介:苏红如（1977-）,女,硕士,副主任医师,E-mail:xyfyfk@163.com;杨忍忍（1993-）,女,在读硕士研究生,E-mail:yangrenren1993@163.com。^*并列第一作者
基金资助:
上海市徐汇区卫生尖峰学科（SHXH201706）

The effect of fluoride varnish Duraphat in preventing deciduous dental caries in preschool children

SU Hong-ru¹, YANG Ren-ren², QIAN Wen-hao¹, YU Jin-ming²

1.Dental Disease Control Institute, Xuhui District. Shanghai 200032;
2.Key Laboratory of Health Technology Assessment of Ministry of Health, Collaborative Innovation Center of Social Risks Governance in Health, School of Public Health, Fudan University. Shanghai 200032, China

Received:2018-08-16 Revised:2018-10-25 Online:2019-02-25 Published:2019-04-12

摘要/Abstract

摘要： 目的:观察氟化钠护齿剂预防儿童乳牙龋齿的效果,为全面开展学龄前儿童涂氟防龋提供依据。方法:采取随机整群抽样方法,在上海市徐汇区抽取25所公办幼儿园3~4岁小班儿童共1140名作为研究对象,在儿童家长知情同意的情况下,本着自愿原则,将研究对象分为2组。涂氟组762名,每半年涂氟1次,连续2年共涂布4次;对照组378名,不做涂氟处理。对所有入组儿童进行口腔卫生指导,比较2组儿童患龋率、龋均、龋病发病率、新增龋均的情况,采用SAS 9.4软件包进行统计学分析。结果:2年后,对照组的患龋率、龋均、龋病发生率和新增龋均均显著高于涂氟组（P<0.05）。结论:在学龄前儿童中应用氟化钠护齿剂,能有效降低乳牙龋病发生率和新增龋均,值得在学龄前儿童中推广应用。

关键词: 氟化钠护齿剂, 多乐氟, 龋病预防, 学龄前儿童

Abstract: PURPOSE: To evaluate the effect of fluoride varnish Duraphat on preventing caries of primary teeth caries, and provide scientific basis for the establishment of oral health care. METHODS: 1140 preschool children aged 3~4 years old were chosen from 25 public kindergartens in Xuhui district of Shanghai by cluster sampling method, they were divided into 2 groups on a voluntary basis with the informed consent of the child's parents. 762 preschool children in Fluoride Varnish group were taken oral examination and used fluoride varnishes every 6 months, 378 preschool children in the control group were without treatment. Oral health instruction was given to all the children. The data of caries prevalence, mean dmft, caries incidence and mean increments of dmft (decayed, missing and filled teeth) of 2 groups were compared. The results were analyzed using SAS 9.4 software package. RESULTS: After 2 years, caries prevalence, mean dmft, caries incidence and mean increments of dmft of fluoride varnish groups were lower than those of control group and the difference was statistically significant (P<; 0.05). CONCLUSIONS: Fluoride varnish Duraphat is effective in decreasing caries incidence and mean dmft increments of primary teeth in preschool children and is worthy to be used widely in Xuhui district.

Key words: Fluoride varnish, Duraphat, Caries prevention, Preschool children

中图分类号:

R780.1

苏红如, 杨忍忍, 钱文昊, 余金明. 氟化钠护齿剂在预防学龄前儿童乳牙龋齿中的疗效观察[J]. 上海口腔医学, 2019, 28(1): 48-42.

SU Hong-ru, YANG Ren-ren, QIAN Wen-hao, YU Jin-ming. The effect of fluoride varnish Duraphat in preventing deciduous dental caries in preschool children[J]. Shanghai Journal of Stomatology, 2019, 28(1): 48-42.

参考文献

[1] Dawkins E, Michimi A, Ellis-griffith G, et al. Dental caries among children visiting a mobile dental clinic in South Central Kentucky: a pooled cross-sectional study[J]. BMC Oral Health, 2013,13(1): 1-9.
[2] Scorca A, Santoro V, De Donno A, et al.Early childhood caries (ECC) and neglect in child care: analysis of an Italian sample[J]. Clin Ter, 2013, 164(5): e365-e371.
[3] Gomes MC, Pinto-Sarmento TC, Costa EM, et al.Impact of oral health conditions on the quality of life of preschool children and their families: a cross-sectional study[J]. Health Qual Life Outcomes, 2014,12(1): 55-67.
[4] Saido M, Asakura K, Masayasu S, et al.Relationship between dietary sugar intake and dental caries among Japanese preschool children with relatively low sugar intake (Japan Nursery School SHOKUIKU Study): A nationwide cross-sectional study[J]. Matern Child Health J, 2016, 20(3): 556-566.
[5] Jain M, Namdev R, Bodh M, et al.Social and behavioral determinants for early childhood caries among preschool children in India[J]. J Dent Res Dent Clin Dent Prospects, 2015, 9(2): 115-120.
[6] 张松杰, 李骏, 毋丹丹, 等. 西安市区881名学龄前儿童乳牙患龋状况及影响因素分析[J]. 中国儿童保健杂志, 2016, 24(4): 434-437.
[7] Oliveira BH, Salazar M, Carvalho DM, et al.Biannual fluoride varnish applications and caries incidence in preschoolers: a 24-month follow-up randomized placebo-controlled clinical trial[J]. Caries Res, 2014, 48(3): 228-236.
[8] Bafti LS, Hashemipour MA, Poureslami H, et al.Relationship between body mass index and tooth decay in a population of 3-6-year-old children in Iran[J]. Int J Dent, 2015,2015:126530.
[9] Skripkina GI, Garifullina AZ.Serial clinical examinations as the main approach to dental caries prevention in children[J]. Stomatologiia(Mosk), 2015, 94(5): 64-66.
[10] 梅银娥, 周春泉, 王向荣, 等. 应用氟化泡沫预防幼儿龋齿的防龋效果观察[J]. 临床口腔医学杂志, 2014, 30(1): 50-51.
[11] 蒋琳, 庄庆明, 王金华, 等. 重庆市学龄前儿童龋病状况调查[J].华西口腔医学杂志, 2014, 32(5): 472-475.
[12] 高祯, 蔡蔚, 霍东婷, 等. 氟保护漆预防学龄前儿童乳牙龋的疗效观察[J]. 中国儿童保健杂志, 2017, 25(5): 519-522.
[13] Mishra P, Fareed N, Battur H, et al.Role of fluoride varnish in preventing early childhood caries: A systematic review[J]. Dent Res J (Isfahan), 2017,14(3):169-176.
[14] 冯汝舟,刘娟, 吕长海. 氟化物在儿童和青少年龋病防治中的应用[J]. 国际口腔医学杂志, 2016, 43(1): 118-122.
[15] Akbar AA, Al-Sumait N, Al-Yahya H, et al.Knowledge, attitude, and barriers to fluoride application as a preventive measure among oral health care providers[J]. Int J Dent, 2018 ,2018: 8908924.
[16] 张露东, 周寅, 朱亚琴. 氟保护漆对儿童第一恒磨牙龋病的预防效果评价[J]. 上海口腔医学, 2017, 26(6): 641-645.
[17] Chen KJ, Gao SS, Duangthip D, et al.Managing early childhood caries for young children in China[J]. Healthcare (Basel), 2018, 6(1): 1-9.
[18] 曹斌,涂斌,刘成军,等.含氟涂料预防学龄前儿童乳牙龋齿效果评价[J].中国学校卫生, 2017, 38(8): 1243-1245.
[19] 缪羽, 张双阳, 于蕴之, 等. 应用生存分析方法随访观察氟保护漆对学龄前儿童龋病的预防效果[J].中国实用口腔科杂志, 2016, 9(10): 600-604.
[20] 刘金蓉,邹廷前.多乐氟(Duraphat)用于预防乳牙继发龋的临床观察[J].临床口腔医学杂志, 2017, 33(10): 628-630.
[21] 宋珏, 曹新明, 吴振刚, 等. 氟化钠护齿剂在预防上海市学龄前儿童龋齿中的效果评价[J].口腔医学, 2017, 37(10): 925-928.
[22] Vogel GL.Oral fluoride reservoirs and the prevention of dental caries[J]. Monogr Oral Sci, 2011, 22(6): 146-157.
[23] 张瑜瑜, 张颖, 和睦, 等. 氟保护漆对学龄前儿童乳磨牙防龋效果评价[J]. 中国实用口腔科杂志, 2016, 9(4): 233-236.
[24] 黄长波. 氟化物防龋和免疫防龋对学龄前儿童龋病的预防效果及对链球菌菌群变化的影响[J]. 中国妇幼保健, 2017, 32(7): 1519-1521.
[25] Seppä L.Fluoride varnishes in caries prevention[J]. Med Princ Pract, 2004,13(6): 307-311.
[26] 吴晨, 徐东升, 赵玉梅. Duraphat varnish对乳牙釉质氟含量的影响[J]. 上海口腔医学, 2011, 20(2): 159-163.

氟化钠护齿剂在预防学龄前儿童乳牙龋齿中的疗效观察

The effect of fluoride varnish Duraphat in preventing deciduous dental caries in preschool children

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